睡眠障碍对中风认知功能的影响:系统性审查和元分析
Yingqiao Wang1, Leyao Han1, Zongyan Man2
1School of Nursing, Lanzhou University, Lanzhou, China.
Behavioral sleep medicine
|August 6, 2025
概括
睡眠障碍显著增加了中风患者认知障碍的风险. 这种风险在老年人中被放大,突出了针对性干预的需要.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 认知科学 认知科学
背景情况:
- 睡眠障碍会对中风恢复产生负面影响,影响生理功能,再入院率和死亡率.
- 睡眠障碍对中风后认知功能的确切影响仍然不一致.
- 这项研究调查了中风幸存者的睡眠障碍和认知障碍之间的联系.
研究的目的:
- 确定睡眠障碍对中风患者认知功能的影响.
- 探索特定类型的睡眠障碍与认知缺陷之间的关系.
- 提供证据,以更好地管理中风患者睡眠障碍的治疗策略.
主要方法:
- 从多个数据库 (PubMed, Cochrane, Web of Science, Embase, CBM, CNKI, Wanfang, VIP) 的研究进行了系统的审查和元分析.
- 包括6项纵向研究和10项横截面研究,涉及5779名患者.
- 使用Revman 5.3进行统计分析,将几率比率 (OR) 和标准化平均差异 (SMD) 与异质性和灵敏性分析相结合.
主要成果:
- 纵向和横截面研究都表明,中风患者患有睡眠障碍更有可能出现认知障碍 (ORs从2.35到2.62).
- 在横截面研究中解决了高异质性问题,在数据精细化后,结果保持一致.
- 晚年被确定为加剧中风患者睡眠障碍负面认知影响的重要因素.
结论:
- 睡眠障碍被证实是导致中风幸存者的认知障碍的相关因素.
- 睡眠障碍对中风患者认知的负面影响随着年龄的增长而变得更加明显.
- 在中风患者,特别是老年人中解决睡眠障碍对于减轻认知衰退至关重要.
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