关于固定食物喷发的审查
Ben W Gratz1, Kareena S Garg1, Ahsan Raza Raja2
1From the Georgetown University School of Medicine, Washington, DC, USA.
Dermatitis : contact, atopic, occupational, drug
|August 6, 2025
概括
固定食物喷发 (FFE) 是一种罕见的皮肤疾病. 这次审查发现,增强水,果仁和花生是常见的触发因素,口腔挑战是主要的诊断方法.
科学领域:
- 皮肤病学 皮肤病学
- 过敏和免疫学 过敏和免疫学
- 药物监督 药物监督 药物监督
背景情况:
- 固定的食物喷发 (FFE) 是一种罕见的皮肤不良药物反应.
- 在摄入特定的食物触发物后,在相同的部位出现反复的皮肤病变的特征.
- 有限的综合性评论存在,需要对当前文献进行综合.
研究的目的:
- 系统地审查和综合有关固定食物喷发的已公布数据.
- 解决了解FFE人口统计,常见触发因素和诊断方式方面的差距.
- 基于现有案例研究,提供FFE的全面概述.
主要方法:
- 在MEDLINE,Embase,Cochrane和Web of Science数据库中的系统文献搜索.
- 在对重复性和相关性进行选后,包括32项研究.
- 提取有关患者人口统计,食物触发因素,发病,诊断和治疗的数据.
主要成果:
- FFE主要影响女性 (63.9%) 和18岁以上的成年人 (73.7%).
- 调味水 (24.1%) 是最常见的触发因素,其次是果仁和花生 (各为8.1%).
- 在67.2%的病例中,病变在4小时内出现;口腔挑战在78.6%的病例中证实了诊断.
结论:
- 本综述提供了FFE数据的首次全面综合.
- 突出了主要的人口趋势,常见的食物触发器,如增强水,和诊断方法.
- 强调避免触发器作为FFE的主要管理策略.
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