揭露健康差异:跨性别队列中的诊断流行率与匹配的对照组相比
Laurel Hiatt1, Blessing S Ofori-Atta2, Amanda V Bakian3
1Department of Human Genetics, University of Utah, Salt Lake City, Utah, United States of America.
PloS one
|August 6, 2025
概括
变性人和性别多元 (TGD) 个体有更高的医学和心理健康状况的记录率. 这些差异可能源于歧视,医疗保健获取差异或真实发病率变化.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 人口健康 人口健康
- 医疗信息学 医疗信息学
背景情况:
- 跨性别和性别多元 (TGD) 的人口面临着严重的健康不平等.
- 关于TGD个体中临床条件的流行情况,人口层面的数据有限.
- 利用大型数据集对于了解TGD健康需求至关重要.
研究的目的:
- 检查与年龄相匹配的一般队列相比,TGD个体的人口水平诊断流行率.
- 利用犹他州人口数据库进行全面的健康记录分析.
- 为了识别医疗,心理健康和神经发育条件的差异.
主要方法:
- 一组6664名TGD个体被使用ICD代码识别为性别不一致 (1995-2021).
- 建立了一个年龄相匹配的对照队列,包括64,124名个人.
- 通过修改Poisson回归,Phecodes被用来分析临床表型的差异.
主要成果:
- 在TGD队列中,医疗,心理健康和神经发育类别的记录患病率较高.
- 在TGD患者中常见的医学诊断包括睡眠障碍和慢性疼痛.
- 在TGD队列中观察到情绪,抑郁,焦虑和人格障碍的患病率显著更高.
结论:
- 这项研究揭示了TGD个体在各种健康领域的显著诊断差异.
- 结果表明潜在的驱动因素包括歧视,医疗保健系统的相互作用和真正的发病率差异.
- 了解这些差异对于改善TGD医疗保健和减少不平等至关重要.
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