在自闭症谱系障碍中的草药:治疗潜力,植物成分和剂量指南
Nasser M Aldekhail1, Hanan Khojah1, Nouf Humoud Alsaadoun2
1Department of Pharmacy, College of Pharmacy, Nursing and Medical Sciences, Riyadh Elm University, Riyadh, Saudi Arabia.
Alternative therapies in health and medicine
|August 6, 2025
概括
本综述总结了关于治疗自闭症谱系障碍 (ASD) 的草药的最新证据. 关键发现突出了像Bacopa monnieri和Curcuma longa这样的草药用于症状管理,强调了标准化剂量和进一步临床试验的必要性.
科学领域:
- 综合医学是一个整体医学.
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 自闭症谱系障碍 (ASD) 在社会沟通和行为方面存在重大挑战.
- 现有的治疗方法通常集中在症状管理上,对补充疗法的兴趣越来越大.
- 缺乏对ASD近期草药研究的全面审查.
研究的目的:
- 综合最近关于草药治疗自闭症谱系障碍 (ASD) 疗效和机制的证据.
- 为了确定关键的生物活性化合物,最佳的剂量策略和潜在的治疗效果.
- 概述ASD中草药干预的临床影响和未来研究方向.
主要方法:
- 采用了叙事审查方法,搜索主要的科学数据库 (PubMed,Scopus,科学网,谷歌学者).
- 包括2018年至2025年中期发表的研究,优先考虑临床试验和临床前研究.
- 纳入标准集中在详细介绍植物化合物,剂量和ASD作用机制的研究上.
主要成果:
- 巴科巴蒙尼利,长黄 (库尔库明) 和绿茶提取物 (卢托林) 显示出对ASD的认知,行为和神经炎症方面有前途.
- 大麻素,金科比洛巴,激情花和根对睡眠,社交参与,循环,焦虑和过度活动都有好处.
- 益生菌发酵草药和阿什瓦甘达显示出对肠-大脑轴和神经保护的潜力,分别.
结论:
- 草药疗法可以为核心ASD症状和相关的并发症提供支持性益处.
- 配方的标准化,严格的剂量和整合方法的进一步验证是必不可少的.
- 大规模的随机临床试验对于确认疗效,安全性和个性化治疗策略至关重要.
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