在使用舌下布诺芬后,口腔癌发生
Annie R Abruzzo1, Miriam T H Harris2, Herve Y Sroussi3
1Harvard Medical School, Boston, MA, USA; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, MA, USA.
本案例报告详细介绍了对阿片类药物使用障碍 (OUD) 和口腔状细胞癌 (OCSCC) 进行语言下布诺芬使用之间的潜在联系. 需要进一步调查以证实这种关联.
科学领域:
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
- 成 药物 药物 药物 药物
背景情况:
- 语言下布伦诺芬是阿片类药物使用障碍 (OUD) 的首要治疗方法.
- 最近的FDA通讯强调了口服溶解布诺芬的牙科问题.
- 之前没有报告将舌下布伦诺芬与口腔癌联系起来.
研究的目的:
- 报告第一个已知的口腔恶性瘤病例,与语言下布诺芬相关.
- 提高医疗保健提供者对潜在风险的认识.
- 建议进一步调查可能的致病作用.
主要方法:
- 一个53岁的女性没有吸烟史的案例报告.
- 详细介绍了口腔状细胞癌 (OCSCC) 在舌下布诺芬放置部位的发展情况.
- 记录了成功的手术治疗和病理阶段.
主要成果:
- 一名患者在13年以后出现了下语言OCSCC,后者使用了下语言布诺芬.
- 癌症确切地位于药物被注射的地方.
- 患者通过pT1N0分期成功实现了手术缓解.
结论:
- 这一案例表明,语言下布诺芬与口腔瘤之间存在潜在的关联.
- 机理和间接证据支持进一步调查.
- 治疗OUD和口腔癌的临床医生应该意识到这种可能的风险.
更多相关视频
08:15A Hepatocellular Cancer Patient-Derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth
Published on: February 2, 2024
07:29Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
相关概念视频
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Drug Delivery: Enteral Route
Oral Cavity
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
