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Updated: Sep 12, 2025

Studying Pre-formed Fibril Induced α-Synuclein Accumulation in Primary Embryonic Mouse Midbrain Dopamine Neurons
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Published on: August 16, 2020

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α-Synuclein驱动SNARE依赖的管状囊泡重塑

Qun Li1,2,3, Tao Hu1, Fan Li1

  • 1Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai, Shandong 264117, China.

Journal of the American Chemical Society
|August 6, 2025
PubMed
概括

阿尔法-同核素 (α-syn) 在突触囊中迅速形成管状突出,需要SNARE蛋白质. 这种新奇的机制有助于帕金森病 (PD) 的突触功能障碍.

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