p53-DNA

Haoxin Sun1, Jingbo Wei2, Yiming Tang3

  • 1School of Mathematics and Computer Sciences, Nanchang University, Xuefu Avenue 999, Nanchang City 330031, China; Institute of Space Science and Technology, Nanchang University, Xuefu Avenue 999, Nanchang City 330031, China.

PubMed
概括

这项研究引入了一种对蛋白质全ostery进行修改的神经关系推理 (NRI) 模型,增强了对p53-DNA相互作用中的远程全osteric通路的预测,并揭示了突变诱导的通信中断.

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