使用压缩来防止血管缩的复发:一个随机的假冒受控试验
Hamed Tavolinejad1, Ali Bozorgi1, Zahra Emkanjoo2
1Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Journal of the American College of Cardiology
|August 6, 2025
概括
在一项随机试验中,大腿高弹性压缩 (ECS) 并没有显著减少血管 (VVS) 的复发. 虽然ECS没有减少整体复发,但在积极佩戴时显示出更少发作的趋势.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學.
- 血管医学 血管医学
背景情况:
- 血管 (VVS) 是一种常见的疾病,有效的治疗选择有限.
- 弹性压缩 (ECS) 是对VVS的拟议疗法,但其实际有效性尚未得到充分证实.
研究的目的:
- 为了比较大腿高弹性压缩 (ECS) 与假在防止VVS复发方面的有效性.
- 评估ECS对无VVS存活率和复发发作的频率的影响.
主要方法:
- 一个多中心的,盲目的,随机的假控制试验,涉及266名成年人 (18-65岁) 具有VVS病史.
- 参与者被随机分配,在标准护理之外接受积极的大腿长ECS (25-30毫米升) 或假ECS (≤10毫米升).
- 主要结局包括VVS复发的参与者比例和12个月内第一次VVS复发的时间.
主要成果:
- 在VVS复发率 (29.1%与34.8%) 或VVS无生存率中,在ECS和假装组之间没有显著差异.
- 对于ECS的坚持是不理想的,并且在各组之间是相似的,停药率很高.
- 当参与者积极佩戴ECS时,VVS事件的统计显著减少 (32.7%与45.1%相比).
结论:
- 在VVS患者中,大腿ECS并没有降低累积发病率或VVS无存活率.
- 这项研究不支持常规使用大腿长度ECS来预防VVS.
- 未来的研究应该探索更广泛的压缩策略,以准骨盆和腹部静脉聚合.
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