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SphK 抑制剂 ZFP-B34 抑制了 TNBC 细胞的生长

Bingqing Cui1,2, Jianming Wei1,2,3, Huiting Peng1,2

  • 1Department of Pharmacy (Shandong Provincial Key Traditional Chinese Medical Discipline of Clinical Chinese Pharmacy), Shandong Cancer Hospital and institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250117, P. R. China.

Biological & pharmaceutical bulletin
|August 6, 2025
PubMed
概括

一种新型化合物ZFP-B34在三阴性乳腺癌 (TNBC) 中有效抑制了斯芬哥辛激酶1/2 (SphK1/2). 这种双重抑制剂阻止了癌细胞的生长和迁移,为TNBC提供了一个有前途的治疗策略.

关键词:
在ZFP-B34中使用.斯芬戈氨酸激酶1/2 (SphK1/2) 是一种三重阴性乳腺癌是什么

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