在患有急性冠状动脉综合征的患者中,心上脂肪组织体积与左心室射出小部分变化之间的关联
Ken Harada1, Masataka Kato1, Satoshi Terashima1
1Department of Cardiology, Chubu Rosai Hospital.
Journal of atherosclerosis and thrombosis
|August 6, 2025
概括
脊心脂肪组织 (EAT) 体积与急性冠状动脉综合征 (ACS) 后左心室喷射率 (LVEF) 的变化无关. 然而,患有慢性心力衰竭且EF降低 (HFrEF) 的患者显示了更高的EAT体积.
科学领域:
- 心脏病学 心脏病学
- 心血管成像 - 心血管成像
- 代谢综合征是代谢综合征的一种.
背景情况:
- 在急性冠状动脉综合征 (ACS) 中,心上脂肪组织 (EAT) 体积升高.
- 在ACS后的EAT体积和左心室 (LV) 改造或喷射分数 (LVEF) 之间的关系尚不清楚.
研究的目的:
- 在ACS后的患者中调查EAT体积和时间LVEF变化之间的关联.
- 探索EAT体积与ACS后不同心力衰竭分类之间的相关性.
主要方法:
- 对197名因ACS住院的患者进行前性队列研究.
- 对143名患者进行了超过三年的心声图谱.
- 患者被归类为心力衰竭,EF降低 (HFrEF),轻度降低EF (HFmrEF) 和保存EF (HFpEF) 组.
主要成果:
- 在ACS后的3年内,初始EAT量和LVEF变化之间没有发现显著的关联.
- 在ACS期间,肌酸酸酶水平的峰值与慢性阶段的LVEF有很强的相关性.
- 与HFmrEF和HFpEF组相比,HFrEF患者表现出最高的EAT体积 (p=0.04).
- 在慢性HFmrEF和HFpEF患者中,EAT体积与体重指数呈正相关性,但在HFrEF患者中并非如此.
结论:
- 在ACS后3年,EAT体积不是LVEF变化的预测指标.
- 患有慢性HFrEF的患者表现出更高的EAT体积,无论肥胖状况如何.
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