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Updated: Sep 12, 2025

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice
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Published on: February 3, 2023

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在脂肪细胞前体细胞中,IRX3控制了一种依赖于SUMOylation的分化开关.

Jan-Inge Bjune1,2,3, Samantha Laber4, Laurence Lawrence-Archer1,3

  • 1Mohn Research Center for Diabetes Precision Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway.

Nature communications
|August 6, 2025
PubMed
概括

通过改变表观遗传重编程和SUMOylation,IRX3蛋白影响细胞命运. 这种调节是维持中酶体身份,促进脂肪储存和抑制骨形成的关键.

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