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Updated: Sep 12, 2025

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
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Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Published on: May 8, 2020

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通过基于外体的治疗进行再生性皮肤重塑:一项案例研究表明,21个月的持续结果在毛孔大小,红疹和超色素化方面

Young Seob Lee1,2,3

  • 1Department of Plastic Surgery, Chung-Ang University College of Medicine, Seoul, Korea. ylee2010@gmail.com.

Dermatology and therapy
|August 6, 2025
PubMed
概括

用微针进行局部外体治疗为皮肤衰老提供了一种安全的再生方法. 这种治疗显著改善了近两年的毛孔大小,红色和色素,证明了长期的面部复发.

关键词:
外体疗法是一种外体疗法.面部红血症 面部红血症长期的结果.梅拉斯玛是什么意思毛孔缩小的情况皮肤复发 皮肤复发表面的微针进行了表面微针.

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Human Ex vivo Wound Model and Whole-Mount Staining Approach to Accurately Evaluate Skin Repair

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Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis09:16

Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
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After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
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