每日饮酒量与高血压患病率之间的关联:来自2007-2018年NHANES数据库的证据
Xiao-Feng Fan1, Hong Xie2, Wen-Huan Shuai3
1Department of Cardiology, Zigong Fourth People's Hospital, 19 Tanmulin Road, Zigong, Sichuan, 643000, P.R. China. fangshekefirst@163.com.
BMC cardiovascular disorders
|August 6, 2025
概括
非常重的酒精消费 (每天超过40克) 与更高的高血压患病率有显著联系. 这凸显了在高血压预防和管理策略中评估酒精摄入量的必要性.
科学领域:
- 心血管健康 心血管健康
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 高血压影响全球数亿人,构成重大公共卫生挑战.
- 虽然已知酒精与高血压的联系,但剂量反应,混因素和人口差异需要进一步澄清.
研究的目的:
- 调查美国成年人每日饮酒和高血压患病率之间的关联.
- 检查潜在的非线性关系,并确定这种关联中的特定人群差异.
主要方法:
- 分析了20岁以上 (2007-2018年) 国家健康和营养检查调查 (NHANES) 参与者的数据.
- 使用加权多变量逻辑回归和限制立方线 (RCS) 来评估酒精与高血压的联系.
- 进行了子组分析,以探索人口统计学变量之间的相互作用效应.
主要成果:
- 在每日饮酒量和高血压患病率之间发现了显著的积极关联 (OR: 1.007,P < 0.001).
- 非常重的酒精消费者 (>40 g/d) 与禁酒者相比,高血压的患病率明显高 (OR: 1.873,P < 0.001).
- RCS分析证实了积极的,非线性关联,在种族/种族子组中发现了显著的相互作用.
结论:
- 非常重的酒精消费与高血压患病率的增加有显著关联.
- 将酒精摄入量评估纳入高血压管理和预防至关重要.
- 对因果关系和生物机制的进一步研究是有必要的.
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