微生物群与宿主相互作用:探索它们的动力学和对人类疾病的贡献
Siau Wui Chin1, Zheng Yao Low1, Wei Qi Tan1
1School of Science, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Subang Jaya, Selangor, Malaysia.
MicrobiologyOpen
|August 7, 2025
概括
细菌失调,肠道,皮肤和口腔微生物群的不平衡,导致各种疾病. 了解这些相互作用对于开发用于IBS和等疾病的新疗法至关重要.
科学领域:
- 微生物学 微生物学
- 人类健康 人类健康 人类健康
- 疾病的病原发生 疾病的病原发生
背景情况:
- 失生症涉及细菌组成的不平衡,导致有益细菌的丧失和潜在的致病性细菌的过度生长.
- 诸如饮食,生活方式,年龄和化学物质暴露等因素对细菌失生症有很大影响.
- 了解细菌动态对于预防和缓解与微生物失衡相关的疾病至关重要.
研究的目的:
- 阐明细菌在维持人类健康中的动态作用.
- 探索细菌-细菌相互作用如何影响抗菌素耐药性的兴起.
- 详细介绍细菌失生症与肠道,皮肤和口腔的特定疾病之间的关系.
主要方法:
- 本综述综合了当前关于细菌失生症及其健康影响的知识.
- 它研究了微生物群落在人体不同部位的复杂关系.
- 该审查讨论了恢复微生物平衡的现有和新兴治疗策略.
主要成果:
- 细菌性失生症与诸如刺激性肠综合征 (IBS),炎症性肠病 (IBD),常见 (AV),阿托皮性皮肤炎 (AD),牙周炎和牙损伤等疾病有关.
- 细菌与细菌之间的相互作用可能在抗菌素耐药性的增加中发挥作用.
- 该审查强调了微生物群在维持宿主健康方面的复杂相互作用.
结论:
- 通过诸如益生菌,益生菌,共生菌,微生物种移植和菌体疗法等干预措施恢复微生物平衡,对于治疗与失能相关的疾病至关重要.
- 对细菌相互作用的进一步研究对于开发新疗法至关重要.
- 了解失生症对于促进人类健康和打击抗菌素耐药性至关重要.
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