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一个模块化聚合物平台,用于癌症免疫治疗中高效的mRNA输送

Guanyou Lin1, Jianxi Huang1, Xinqi Li1

  • 1Department of Materials Science and Engineering, University of Washington, Seattle, Washington 98195, USA. mzhang@uw.edu.

Nanoscale horizons
|August 7, 2025
PubMed
概括

一种新的聚合物纳米平台,PFHA-PEI-mRNA-HP,增强了用于癌症基因治疗的信使RNA (mRNA) 传递. 与脂质纳米颗粒 (LNP) 相比,该平台显示出更高的效率和稳定性,在临床前模型中显著抑制瘤生长.

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