机械血栓切除和导管导向溶解治疗中级风险肺栓塞:30天的结果
Nicolas W Shammas1, William Sharis1, George Mankarious1
1Division of Cardiovascular Research, Midwest Cardiovascular Research Foundation, Davenport, Iowa.
概括
透皮机械血栓切除术 (PMC) 通过减少右心室应变,有效治疗中等风险肺栓塞 (IRPE). 无论是FlowTriever还是Ekos设备都显示出类似的安全性和有效性,Ekos提供更短的手术时间.
科学领域:
- 心脏病学 心脏病学
- 干预性放射学 干预性放射学
- 肺部医学 肺部医学
背景情况:
- 中级风险肺栓塞 (IRPE) 涉及右心室 (RV) 应变和心肌缩.
- 针对IRPE的最佳穿皮机械血栓切除术 (PMC) 装置需要进一步进行比较分析.
研究的目的:
- 为了比较FlowTriever和Ekos PMC设备在治疗IRPE中的性能和安全性.
- 评估PMC对RV/LV比率和肺动脉 (PA) 压力的影响.
主要方法:
- 在2019-2022年期间,对97名IRPE患者进行了FlowTriever或Ekos设备治疗的回顾性审查.
- 主要终点:RV/LV比率的变化. 二级终点:手术并发症,30天死亡率和严重出血.
主要成果:
- 与基线相比,PMC显著降低了RV/LV比率和PA压力 (p < 0.0001).
- 在FlowTriever和Ekos之间,有效性或安全性 (30天死亡率,严重出血) 没有显著差异.
- 埃科斯证明了更短的手术时间,更少的光学和减少对比度的使用.
结论:
- 无论是FlowTriever还是Ekos都是IRPE有效的PMC设备,具有可比的临床结果.
- 设备的选择可以考虑程序效率因素,如程序时间和资源利用.
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