成人重症监护室的催化性戒断综合征:一个范围审查
Emanuel Moisa1,2, Georgeana Tuculeanu1,2, Dan Corneci2,3
13rd Department of Anesthesiology and Critical Care, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Frontiers in medicine
|August 7, 2025
概括
成人重症监护室 (ICU) 中的阳性性戒断综合征 (IWS) 研究不足,诊断,危险因素和结果的发现不一致. 需要进一步的研究,以制定对这种危急状况的指导方针.
科学领域:
- 关键护理医学 关键护理医学
- 药理学 药理学是指药理学的学科.
- 患者安全 患者安全
背景情况:
- 催眠性戒断综合征 (IWS) 是严重病患者突然停止使用阿片类药物/催眠的已知并发症.
- 虽然在儿科患者群体中有记录,但在成人重症监护室 (ICU) 中IWS的证据有限.
- 这种稀缺性阻碍了有效的诊断,治疗和预防策略.
研究的目的:
- 进行对严重病情的成年患者IWS现有证据的范围审查.
- 绘制有关IWS诊断,流行病学,危险因素,并发症,临床影响,治疗和预防的当前知识.
- 确定关键的知识差距和需要进一步调查的领域.
主要方法:
- 在PubMed,Scopus和Web of Science进行了全面的文献搜索,搜索了1990年至2024年间发表的研究.
- 包括的研究设计是前性,后性或随机对照试验.
- 29项研究符合超过3105个检索的标题中包含的标准.
主要成果:
- 大多数研究都集中在IWS诊断和流行病学上,经常调整慢性药物使用者的定义;发病率在13.6%至49.5%之间.
- 确定了与治疗相关的风险因素,但很少进行可靠的统计分析.
- 有限的研究涉及治疗/预防,克洛尼丁显示了潜在的益处,但整体结果和ICU/医院结果不一致.
结论:
- 对于管理成人ICU中的IWS存在重大知识差距和缺乏共识/指南.
- 进一步进行高质量的研究对于改善患者护理和治疗结果至关重要.
- 迫切需要标准化的诊断标准和基于证据的治疗方案.
关键词:
作为一种类药物,它是 benzodiazepine.克洛尼迪因 (clonidine) 是一种类型的药物.德克斯梅德特-奥米丁的使用情况催眠术是一种催眠术.催产剂性戒断综合征是什么意思这是一种阿片类阿片类药物.镇静 镇静是一种镇静.更多相关视频
06:04Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex
Published on: July 4, 2018
9.0K
10:38Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
Published on: January 16, 2019
20.4K
相关概念视频
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.4K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.4K
01:29Acute Kidney Injury III: Clinical Manifestations
94
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
94
01:22Acute Kidney Injury VI: Nursing Management
59
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
59
01:22Acute Kidney Injury I: Introduction
74
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
74
01:20Acute Kidney Injury V: Interprofessional Care
45
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
45
01:30Acute Pancreatitis II: Clinical Manifestations and Management
177
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
177