Judith Münch1, Jordi Soler2, Ofir Gildor-Cristal3

  • 1Institute of Chemistry, Martin Luther-University Halle-Wittenberg, Weinbergweg 22, Halle (Saale) 06120, Germany.

ACS catalysis
|August 7, 2025
PubMed
概括

计算式酶设计迅速创造了50种不特定的过氧酶 (MthUPO) 变体,具有增强的烯氧功能. 这些设计的酶显著提高了活性,选择性和新产品合成,在各种应用中表现优于野生类型.

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Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

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Epoxidation of alkenes via oxidation with peroxy acids involves the conversion of a carbon–carbon double bond to an epoxide using the oxidizing agent meta-chloroperoxybenzoic acid, commonly known as MCPBA. Since the O–O bond of peroxy acids is very weak, the addition of electrophilic oxygen of...
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