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Updated: Sep 12, 2025

Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice
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低氧诱导的米托基因因子/RELM-β与骨形态遗传蛋白受体2复合物的结合促进了肺高血压

Ting Zhang1,2,3, Liping Zhu1,2,4,5, Bingxun Liu1,2

  • 1Department of Pathophysiology, School of Basic Medicine (T.Z., L.Z., B.L., J.L., X.Z., W.Y., R.X., Q.H.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Arteriosclerosis, thrombosis, and vascular biology
|August 7, 2025
PubMed
概括

缺氧诱导的代因子 (HIMF) 直接结合BMPR1A,破坏BMPR1A/BMPR2复合体的形成和活动,导致肺高血压. 针对这种相互作用,为肺高血压提供了潜在的治疗策略.

关键词:
骨形态遗传性蛋白质受体2 骨型遗传性蛋白质受体2缺氧诱导的米托基因因子因子肺高血压是一种肺高血压.

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