慢性炎症持续时间在与年龄相关的听力损失中的作用:一个横截面研究
Nezaket Tektaş1, Mehmet İlhan Şahin1, Aslıhan Oflaz Çapar1
1Department of Otorhinolaryngology, Erciyes University School of Medicine, Kayseri, Türkiye.
Acta oto-laryngologica
|August 7, 2025
概括
慢性炎症性疾病会加剧与年龄相关的听力损失,特别是随着疾病持续时间的延长. 扩展的高频听力受到显著影响,突出了炎症和听力健康之间的联系.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 老年学是指老年学的学科.
- 免疫学 免疫学 免疫学
背景情况:
- 与年龄有关的听力损失 (ARHL) 在老年人群中越来越令人担忧.
- 慢性炎症疾病越来越多地被认为是影响多个器官的全身性疾病.
- 慢性炎症与听觉系统完整性之间的相互作用,特别是在老年人中,需要进一步研究.
研究的目的:
- 为了检查慢性炎症疾病和与年龄相关的听力损失之间的关系.
- 为了确定炎症状况的持续时间和同时发生是否会影响听力值.
- 评估60岁以上个体对延长高频听力的影响.
主要方法:
- 这是一项涉及583名60岁以上参与者的横截面研究.
- 在健康队列 (n=65) 和炎症队列 (n=518) 之间进行比较,至少有一种慢性炎症条件.
- 扩展高频音频计 (125-18000 Hz) 和回归分析控制年龄和吸烟史.
主要成果:
- 与健康个体相比,患有慢性炎症疾病的参与者在延长的高频率下显示出明显更高的听力值.
- 慢性炎症疾病的持续时间较长与高频率 (4000-12500 Hz) 的听力值升高显著相关,不依赖年龄.
- 存在多种同时发生的炎症状况并没有显著影响听力值.
结论:
- 慢性炎症疾病的持续时间加剧了与年龄相关的听力损失,特别是在更高的频率下.
- 慢性炎症似乎加快了老年人的听力衰退.
- 针对炎症持续时间可能对于在老年人群中保持听力至关重要.
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