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Updated: Sep 12, 2025

Activated Cross-linked Agarose for the Rapid Development of Affinity Chromatography Resins - Antibody Capture as a Case Study
07:53

Activated Cross-linked Agarose for the Rapid Development of Affinity Chromatography Resins - Antibody Capture as a Case Study

Published on: August 16, 2019

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提高快速蛋白A在单克隆抗体处理中的性能:阳离子交换染色学澄清

Andrew Vail1, David Chau1, Jennifer Heitkamp1

  • 1Purification and Filtration Business, Solventum, St. Paul, Minnesota, USA.

Biotechnology progress
|August 7, 2025
PubMed
概括

澄清用离子交换 (AEX) 纤维进行的中国仓鼠卵巢 (CHO) 细胞培养提高了单克隆抗体 (mAb) 纯度,并与深度过相比显著延长了蛋白A染色学周期. 这提高了生物制药净化过程.

关键词:
蛋白质A染色体的染色学离子交换的离子交换生物处理生物处理.染色学澄清 染色学澄清这是一个澄清,澄清.减少杂质的减少.

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Affinity Chromatography01:03

Affinity Chromatography

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Ion Exchange

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Immunoprecipitation01:20

Immunoprecipitation

Immunoprecipitation, or IP, is a widely used technique that employs protein-antibody interactions to isolate proteins or protein complexes in their native state for studying protein-protein interactions, quaternary structures, or supramolecular complexes. Various modifications of the technique, including chromatin IP, cross-linking IP, and fluorescence IP, are commonly used.
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