儿科重症监护期间红细胞输血:2023年在三个欧洲国家进行28天的点患病率研究
Laura Butragueño-Laiseca1,2,3,4, Samiran Ray5, Avishay Sarfatti6
1Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
概括
在欧洲儿科重症监护室 (PICU),12.8%的儿童接受红细胞输血,主要是基于血红蛋白水平而不是临床触发因素. 这突显了输血实践的变化和潜在的优化领域.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 输血药物 输血药物 输血药物
- 血液学 血液学 血液学
背景情况:
- 红细胞 (RBC) 输血在儿科重症监护室 (PICU) 很常见.
- 关于输血触发因子,特别是血红蛋白值的做法可能会有很大差异.
- 优化红细胞输血协议对于患者的治疗结果至关重要.
研究的目的:
- 确定三个欧洲国家的重症儿童中红细胞输血的患病率.
- 分析血红蛋白值,临床触发因素和与PICU患者的红细胞输血相关的结果.
- 确定改善儿科重症监护中的输血策略的潜在领域.
主要方法:
- 在2023年进行的一项国际4周点患病率研究.
- 从西班牙,英国和意大利的44个PICU收集的数据.
- 纳入标准:1个月至17岁的PICU患者接受红细胞输血.
主要成果:
- 在2713名儿科患者中,有12.8%接受了至少一次红细胞输血.
- 血红蛋白水平是输血的主要指示 (54.6%),通常超过7.0g/dL.
- 输血前血红蛋白水平的中位数因国家而异 (7.8-8.9 g/dL),其他临床触发因素的使用有限.
结论:
- 红细胞输血在欧洲PICU中很普遍,血红蛋白水平经常决定输血决定.
- 目前的输血实践往往超过推值,很少考虑其他临床触发因素.
- 标准化血红蛋白值和采用以目标为导向的策略,可以优化重症儿童的红细胞输血实践.
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