在患有遗传性出血性长管切除症相关的表症患者的硬化疗法上达成共识
Paolo Farneti1, Sol Marcos-Salazar2, Claudia Crocione3
1Department of Otorhinolaryngology, Ospedale Bellaria, Dip. Chirurgie Specialistiche, AUSL Bologna, Bologna, Italy.
JAMA otolaryngology-- head & neck surgery
|August 7, 2025
概括
硬化疗法是安全和有效的遗传性出血端膜病 (HHT). 专家共识提供了30个陈述,以指导安全的患者护理和对这种HHT治疗的程序实施.
科学领域:
- 血管医学 血管医学
- 最少侵入性手术的方法
背景情况:
- 硬化疗法有效地治疗来自鼻腔,口腔和皮肤端膜切除的出血.
- 遗传性出血端膜切开症 (HHT) 患者可以从硬化疗法中受益,但其采用是有限的.
- 需要促进HHT患者安全和广泛使用硬化疗法.
研究的目的:
- 为了实现专家的共识,安全和有效的使用硬化疗法,为患者HHT.
- 开发基于证据的陈述,指导临床医生在HHT的硬化疗法过程中.
主要方法:
- 一个经过修改的Delphi协议,涉及6名国际专家,在HHT硬化疗法方面拥有超过10年的经验.
- 在线会议和谷歌表格调查被使用了3轮,并进行了面对面的讨论以解决分歧.
- 共识被定义为6位小组成员中的4位在7个领域的30个陈述上达成一致.
主要成果:
- 专家们达成共识,稳定的HHT患者有资格接受单个预防措施的硬化疗法.
- 办公室内硬化疗法提供了诸如快速访问和高患者满意度等优势,通常具有轻微的不良影响.
- 制定了针对患者准备 (例如,抗生素预防),并发症预防 (例如,隔膜穿孔) 和从业人员培训的具体建议.
结论:
- 专家共识产生了30个陈述,以指导患者护理和HHT的安全硬化疗法实施.
- 这些陈述为考虑或改进硬化疗法协议的临床医生提供了宝贵的见解.
- 鼓励进一步的研究来验证这些共识陈述,并改善患者在HHT管理中的结果.
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