目前的吸烟和二手烟暴露与英国成年人的慢性术后疼痛有关:一项队列研究
Bin Xu1,2, Lingxiao Chen3,4,5, Maja R Radojčić5
1Cheeloo College of Medicine, The Second Hospital of Shandong University, Shandong University, Jinan, Shandong, People's Republic of China.
International journal of surgery (London, England)
|August 7, 2025
概括
暴露于二手烟 (SHS) 和目前的吸烟显著增加了慢性术后疼痛 (CPSP) 的风险. 暴露于SHS可能与活跃吸烟一样有害,对开发CPSP.
科学领域:
- 疼痛医学 医学 疼痛医学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 慢性手术后疼痛 (CPSP) 显著影响患者的生活质量,并产生大量的医疗保健费用.
- 吸烟是慢性疼痛的一个已知的因素,但它在CPSP中的特定作用,包括二手烟 (SHS) 暴露,需要进一步澄清.
研究的目的:
- 调查当前吸烟,SHS暴露和发展CPSP的风险之间的联系.
- 提供综合分析,考虑各种吸烟分类和SHS暴露.
主要方法:
- 一项使用英国生物库数据从2006-2010年和2019-2020年间手术的队列研究.
- 参与者被分为没有SHS暴露的不吸烟者,有SHS暴露的不吸烟者和目前吸烟者.
- 使用后勤回归模型来评估CPSP的风险,并对社会人口统计学变量进行子组分析.
主要成果:
- 在97,821名参与者中,3.6%的人报告CPSP.
- 与没有SHS暴露的非吸烟者相比,SHS暴露 (OR 1.30,95%CI [1.19至1.41]) 和目前吸烟 (OR 1.37,95%CI [1.22至1.55]) 都与CPSP的风险增加有关.
- 这种增加的风险在各种社会人口统计学子组中是一致的,包括男性和女性.
结论:
- 接触二手烟对慢性手术后疼痛的发展构成重大风险.
- 暴露于SHS对CPSP风险的有害影响似乎与目前吸烟的有害影响相当.
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