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Updated: Sep 12, 2025

Analysis of Non-Human Primate Pancreatic Islet Oxygen Consumption
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人类胰腺小岛功能障碍的分子机制 在营养过度下代谢压力

Xue Hu1, Li Guo2, Maria Pilar Toledo2

  • 1Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL.

Diabetes
|August 7, 2025
PubMed
概括

过度营养会导致胰腺小岛细胞的代谢压力,使得β细胞比α细胞更脆弱. 基因组甲基转移酶G9a和GLP是贝塔细胞对这种压力的反应的关键,为2型糖尿病提供了潜在的治疗点.

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