在资源有限的环境中,癌症儿童的浪费和短期结果:乌干达的一项前性研究
Richard Nyeko1,2, Jaques van Heerden2,3, Joyce Balagadde Kambugu2
1Department of Pediatric and Child Health, Faculty of Medicine, Lira University, Lira, Uganda.
PloS one
|August 7, 2025
概括
在缺乏资源的环境中,癌症儿童中浪费是常见的,视觉评估是不可靠的. 标准的人类测量评估对于准确的诊断和改善结果至关重要.
科学领域:
- 儿科瘤学 儿科瘤学
- 全球健康 全球健康
- 营养科学 营养科学
背景情况:
- 浪费对儿童的癌症治疗结果产生重大影响,特别是在资源有限的地区.
- 在儿童癌症患者中常规,系统地评估消耗的情况往往是不充分的.
- 消耗的视觉诊断是主观的,容易产生偏见.
研究的目的:
- 在乌干达癌症研究所 (UCI) 确定患有癌症的儿童中诊断时消耗的患病率.
- 与人体测量测量相比,评估"可见的浪费"的诊断准确性.
- 在六个月内确定负面结果的预测因素.
主要方法:
- 一项前性研究评估了消耗状态,可见消耗的诊断准确性和UCI新诊断的儿科癌症患者的6个月结果.
- 数据收集时间为2022年4月至2023年3月.
- 统计分析包括描述性,双变量,多变量和生存分析 (P<0.05).
主要成果:
- 在144名儿童中,有39.6%的人类测量定义为消耗,而只有22.2%的儿童表现出明显的消耗.
- 可见的消耗具有低灵敏度 (43.9%),缺少56.1%的消耗儿童.
- 被遗弃的儿童患中性质衰竭 (OR 3.63),败血症 (OR 4.50) 和死亡率 (OR 3.08) 的风险明显更高.
结论:
- 在这种情况下,儿童癌症患者中浪费是普遍存在的,并且与并发症和死亡风险的增加有关.
- 依靠视觉评估来判断消耗是不够的,并导致诊断不足.
- 标准的人类测量评估对于所有儿科癌症患者的精确浪费评估至关重要.
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