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Updated: Sep 12, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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一个瘤特异的膜蛋白降解平台通过共价反应诱导的聚合

Yinsheng Xu1,2, Yingjin Zhang2, Benli Song2

  • 1School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300400, China.

ACS applied materials & interfaces
|August 7, 2025
PubMed
概括

新的共价膜蛋白聚合物向仿真体 (CMPATACs) 能够在不依赖特定受体的情况下降解瘤特异性蛋白质. 这种方法降解了各种细胞表面蛋白质,增强了针对更广泛的治疗应用的抗癌能力.

关键词:
癌症治疗疗法 癌症治疗一种共价反应.lysosomes 溶解体 溶解体 是一种溶解体.膜蛋白降解降解的过程自组装的可以自组装.

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