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肝细胞癌的响应评估:放射科医生的一本书

Nayla Mroueh¹, Jinjin Cao¹, Shravya Srinivas Rao¹

¹Department of Radiology, UPMC, Pittsburgh, PA Massachusetts General Hospital, Harvard Medical School, Boston, MA.

Journal of computer assisted tomography

|August 7, 2025

概括

肝细胞癌 (HCC) 诊断和治疗反应评估正在发展. 本综述涵盖了当前的标准,新兴的成像技术,以及改善HCC管理的未来方向.

科学领域:

肝病学和瘤学肝病学和瘤学
放射学和医学成像学医学成像学

背景情况:

肝细胞癌 (HCC) 是全球主要的癌症负担,需要精确的诊断和反应评估工具.
传统的形态学标准 (WHO,RECIST) 正在被评估可行的瘤负担 (EASL,mRECIST,LI-RADS) 的方法所取代.

研究的目的:

为评估肝细胞癌治疗反应的现有和新兴方法提供全面的概述.
讨论各种响应评估标准的优点和局限性.
探索先进的成像和人工智能在HCC反应评估中的作用.

主要方法:

对HCC现有的反应评估标准的审查,包括形态学和以生存能力为中心的方法.
讨论功能成像技术 (双能CT, perfusion成像) 和放射学.
在成像数据分析中探索人工智能和机器学习应用.

主要成果:

从形态学的转变为以生存能力为重点的标准的演变反映了HCC疗法的进步.
功能成像和放射学为响应评估提供了增强的能力.
人工智能和机器学习有望提高HCC响应评估的精度.

结论:

对HCC治疗反应的准确和早期评估对于患者的治疗结果至关重要.
新兴的成像技术和人工智能有望显著提升HCC反应评估.
对新标准和新技术的持续研究对于优化HCC管理至关重要.

关键词:

李-拉德斯的轨道双能量CT是双能量CT.肝细胞癌是肝细胞癌.莫雷西斯主义者 (mRECIST)perfusion 图像成像输液成像输液成像治疗反应评估治疗反应评估.

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