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Updated: Sep 12, 2025

Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting
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高度保存的贝塔冠状病毒序列被人类T细胞广泛识别

Tertuliano Alves Pereira Neto1, Christian Zmasek2, Liliana Avalos1

  • 1Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.

Cell
|August 7, 2025
PubMed
概括

开发针对SARS-CoV-2等贝塔冠状病毒的广泛免疫力需要准保存的T细胞表位区域 (CTER). 在疫苗中包括非尖端蛋白质可以增强对各种冠状病毒的交叉反应性和覆盖性.

关键词:
贝塔冠状病毒冠状病毒一个T细胞标记物免疫性区域疫情防控工作序列的保存疫苗的使用

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Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
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