多发性硬化症儿童和青少年获得治疗:预防疾病进展的全球性考虑
E Ann Yeh1, Helen Tremlett2, Rabporn Suntornlohanakul3
1Division of Neurology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada; Program in Neuroscience and Mental Health-SickKids, Toronto, ON, Canada; Research Institute, University of Toronto, Toronto, ON, Canada.
The Lancet. Child & adolescent health
|August 7, 2025
概括
患有儿科发病多发性硬化症的儿童在获得重要疗法方面面临重大障碍. 本次审查强调了区域差异,并提出了在这个弱势群体中获得公平待遇的解决方案.
科学领域:
- 神经学 神经学
- 儿科 儿科 儿科
- 公共卫生 公共卫生
背景情况:
- 儿科发病的多发性硬化症 (MS) 影响了一小部分但显著的年轻人群.
- 它与严重的长期运动和认知缺陷,抑郁和疲劳有关.
- 改变疾病的疗法在治疗儿科多发性硬化症方面表现有前途,但获得治疗仍然是一个挑战.
研究的目的:
- 审查关于儿童和青少年患有儿科发病性多发性硬化症的治疗机会的文献.
- 识别阻碍公平获得治疗的障碍.
- 提出改善治疗准入的未来方向.
主要方法:
- 发表的研究的综合文献综述.
- 分析治疗可用性的区域差异.
- 检查影响获得护理,诊断和保险的因素.
主要成果:
- 对于儿童患者的多发性硬化疗法的可用性存在显著的区域差异.
- 障碍包括延迟诊断,不同的监管批准,保险限制和不同的政府支持.
- 不平等的护理机会对患有多发性硬化症的儿童的长期结果产生影响.
结论:
- 解决儿童多发性硬化症治疗机会的差异至关重要.
- 需要改变政策和改进支持系统,以确保平等待遇.
- 未来的努力必须集中在克服所有年轻MS患者所识别的障碍.
相关概念视频
01:28Drug Therapy
100
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
100
01:26Modeling in Therapy
149
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
149
01:20Myasthenia Gravis: Overview and Treatment
1.9K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.9K
01:24Treatment Strategies for Psychological Disorders
271
Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
271
01:19Autism Spectrum Disorder
338
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
338
01:26Group Therapy
86
Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
86