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Updated: Sep 12, 2025

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代SCRaMbLE用于工程合成基因组模块和染色体

Xinyu Lu1,2, Klaudia Ciurkot1,2, Glen-Oliver F Gowers1,2

  • 1Imperial Centre for Engineering Biology, Imperial College London, London, UK.

Nature communications
|August 7, 2025
PubMed
概括

人造酵母基因组正在使用SCRaMbLE (Synthetic Chromosome Recombination and Modification by LoxPsym-mediated Evolution) 进行重新设计,以提高功能. 代的SCRaMbLE循环和一个新的报告系统 (SCOUT) 实现了数据驱动的基因组设计和优化.

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