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赋予抗真菌药物耐药性的RNAi表是可以遗传的

Carlos Pérez-Arques1, María Isabel Navarro-Mendoza2,3,4, Ziyan Xu5

  • 1Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA. carlos.parq@duke.edu.

Nature communications
|August 7, 2025
PubMed
概括

在真菌中赋予抗真菌药物耐药性的表皮突变可以通过小RNAs (sRNAs) 通过几代人传承下来. 这种RNA介导的遗传独立于DNA序列和孟德尔遗传学.

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