学前儿童过敏性鼻炎的危险因素:元分析和系统审查
Nannan Si1,2,3, Wei Chang2, Fengli Cheng1,3
1Department of Otolaryngology Head and Neck Surgery, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, China.
BMC pediatrics
|August 7, 2025
概括
父母过敏,男性性别和潮湿的家庭增加了幼儿过敏性鼻炎 (AR) 的风险. 相反,在家里养物可能会防止AR的发展.
科学领域:
- 儿科 儿科 儿科
- 过敏学 过敏学
- 环境健康 环境健康
背景情况:
- 过敏性鼻炎 (AR) 显著影响学龄前儿童的生活质量.
- 识别AR风险因素对于早期诊断和预防至关重要.
研究的目的:
- 进行元分析,确定和总结学龄前儿童过敏性鼻炎的危险因素.
主要方法:
- 在2025年1月之前对主要数据库进行系统的文献搜索.
- 包括10个队列研究,其中包括94,774名学龄前儿童.
- 随机效应模型用于计算组合赔率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 父母过敏性鼻炎 (OR=2.4),湿疹 (OR=1.72),喘 (OR=2.45) 与AR风险增加有关.
- 男性性别 (OR=1.54),剖腹产 (OR=1.32) 和家庭潮湿 (OR=1.24) 也增加了AR的几率.
- 物在家中的存在显示出保护作用,降低AR风险 (OR=0.57).
结论:
- 父母过敏史,男性性别,剖腹产和潮湿的环境是儿童AR的潜在危险因素.
- 拥有物可能有助于防止过敏性鼻炎的发生.
- 研究结果强调了基因和环境影响对儿科过敏性鼻炎的相互作用.
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