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Updated: Sep 12, 2025

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瘤突变负担高的乳腺癌的基因组特征

Theodore Vougiouklakis1, Chad Vanderbilt1, Satshil Rana1

  • 1Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

NPJ precision oncology
|August 7, 2025
PubMed
概括

乳腺癌中的高瘤突变负担 (TMB) 通常与APOBEC签名和特定基因变异有关. 了解这些基因组特征可能会改善对免疫检查点阻塞疗法的反应.

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