童年创伤和大麻使用对偏执症的影响:结构方程模型方法
Giulia Trotta1, Edoardo Spinazzola2, Hannah Degen2
1Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Psychological medicine
|August 8, 2025
概括
童年创伤显著增加了偏执,大麻使用放大了这些影响. 标准化四大麻 (THC) 单元可以帮助识别受创伤影响的个体的风险.
科学领域:
- 精神病学是一个精神病学.
- 心理学 心理学 心理学
- 大麻研究 大麻研究
背景情况:
- 童年创伤是精神病,偏执和药物使用的已知风险因素.
- 大麻使用是一种可修改的环境因素,可以加剧这些脆弱性.
- 这项研究探讨了童年创伤,大麻消费和偏执之间的复杂关系.
研究的目的:
- 为了检查童年创伤,大麻使用和偏执之间的相互作用.
- 使用标准四大麻 (THC) 单位量化大麻暴露.
- 通过结构方程建模 (SEM) 来评估这些因素之间的直接和间接路径.
主要方法:
- 来自Cannabis&Me在线调查的4736名参与者的数据.
- 儿童创伤的评估使用修改的儿童创伤屏幕问卷.
- 用绿色偏执思想尺度测量偏执.
- 通过每周标准THC单位量化大麻使用量化.
- 使用结构方程建模 (SEM) 进行分析.
主要成果:
- 童年创伤,特别是情绪和身体虐待,与偏执症有很强的相关性.
- 大麻使用,以标准THC单位衡量,显著预测偏执.
- 在THC单位和情绪虐待/家庭冲突之间发现了相互作用.
- SEM表明,创伤对大麻使用中介的偏执症有显著的间接影响.
结论:
- 童年创伤是偏执的主要驱动因素,大麻使用加剧了其影响.
- 大麻使用在创伤-偏执关系中起着重要的调解作用.
- 标准化THC单位对于风险检测和对受创伤影响的个体进行干预非常有价值.
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