侵蚀性食道炎与韩国劳动年龄人群的睡眠问题之间的关系
Sung Keun Park1, Yeongu Chung2, Chang-Mo Oh3
1Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Gut and liver
|August 8, 2025
概括
侵蚀性食道炎 (EE) 与男性的睡眠质量降低,睡眠时间延长和睡眠中断有关. 这种关联在女性中没有观察到,这表明EE对睡眠的性别特异性影响.
科学领域:
- 胃肠病学 胃肠病学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 胃食道逆流性疾病 (GERD) 对睡眠产生负面影响.
- 侵蚀性食道炎 (EE) 和睡眠障碍之间的关系尚不清楚.
研究的目的:
- 调查EE与各种睡眠参数之间的关联.
- 探索EE与睡眠关系中的潜在性别差异.
主要方法:
- 一项针对335,883名接受上部内镜检查的韩国成年人的大规模研究.
- 匹兹堡睡眠质量指数 (PSQI) 用于评估睡眠质量.
- 使用多变量后勤回归分析来确定关联,根据EE严重程度 (洛杉矶分类) 进行子组分析.
主要成果:
- 在男性 (11.1%) 的EE患病率高于女性 (1.8%).
- 在男性中,EE与睡眠质量差 (调整的OR,1.04),更长的睡眠诱导时间 (调整的OR,1.10) 和睡眠中断 (调整的OR,1.11) 相相关.
- 这些关联甚至在轻度EE (LA-A分类) 的男性中也显著,但在女性中没有观察到.
结论:
- 在男性中,EE与睡眠质量差,睡眠诱导时间长和睡眠中断的可能性略有增加有关.
- 这些发现表明,EE和睡眠障碍之间存在性别特异的关系.
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