在医疗保健中对母婴链接算法的审查数据来源
Melanie H Jacobson1, Alexis A Krumme1, Dina M Gifkins1
1Global Epidemiology, Janssen Research and Development LLC, Titusville, New Jersey, USA.
Pharmacoepidemiology and drug safety
|August 8, 2025
概括
连接母亲和婴儿健康记录对于研究婴儿结果至关重要. 这次审查发现了全球多样化的方法,重要记录和出生登记册改善了链接成功,以改善药理学流行病学研究.
科学领域:
- 药学流行病学 药学流行病学
- 医疗信息学 医疗信息学
- 数据链接数据链接
背景情况:
- 在母亲使用药物后评估婴儿健康结果需要将母亲和婴儿的健康记录联系起来.
- 现有的链接方法各不相同,缺乏用于研究的全面评估.
研究的目的:
- 系统地审查和描述用于在医疗保健数据库中链接母婴记录的方法.
- 为了告知在药理流行病学中使用不同链接策略的适应性.
主要方法:
- 进行了多个Medline搜索,并审查了关键论文的参考部分.
- 来自114个出版物 (1990-2025) 的数据来源,链接领域,方法和评估结果的抽象数据.
主要成果:
- 在全球范围内,链接方法各不相同,行政索赔数据的成功率为56%-90%.
- 将生命记录 (例如出生证明) 或出生记录与医院数据相结合,将链接比例分别提高到超过86%和90%.
- 概率方法通常比确定性方法实现更高的链接率,尽管验证并不频繁.
结论:
- 成功的母婴数据连接在全球范围内是可行的,得到了强大的医疗保健基础设施和政策的支持.
- 研究人员应报告联系方法,成功率和有效性评估,以提高对药物流行病学发现的信任.
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