在1990年至2021年期间,高收入国家对心房/病负担的时间趋势分析
Yuqiao Pang1, Hui Li1, Yuyao Zhang1
1Department of Cardiology, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, 646000 Luzhou, Sichuan, China.
Reviews in cardiovascular medicine
|August 8, 2025
概括
在欧盟15+国家,心房动和心房动疾病负担下降,性别和国家特异性差异显著. 老年女性面临更高的风险,需要加强管理策略.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 心房动和心房动 (AF/AFL) 构成重大健康风险,特别是在老年人群中.
- 全球老龄化趋势加剧了AF/AFL发病率和死亡率,观察到的性别差异带来了公共卫生挑战.
- 这项研究调查了高收入欧盟15+ (EU15+) 国家的AF/AFL疾病负担趋势.
研究的目的:
- 分析从1990年到2021年欧盟15+国家的心房和心房 (AF/AFL) 疾病负担的趋势.
- 为了确定AF/AFL发病率和死亡率的性别特异性差异.
- 探索影响AF/AFL疾病负担趋势的因素,包括治疗进步和医疗保健系统变化.
主要方法:
- 利用了全球疾病负担研究 (GBD 2021) 数据,按性别分类年龄标准化发病率和死亡率 (ASIR/ASMR).
- 雇佣的joinpoint回归和年龄时期队列 (APC) 模型,以评估发病率趋势及其决定因素.
- 计算死亡率-发病率指数 (MII) 以进一步分析疾病负担动态.
主要成果:
- 在大多数EU15+国家中观察到AF/AFLASIR和ASMR的总体下降趋势,国家间差异很大.
- 男性的AF/AFL发病率和死亡率通常高于女性,但老年女性与老年男性相比风险增加.
- 治疗的进步,包括抗凝固疗法,射频剥离和新的节律控制药物,影响了疾病负担的变化.
结论:
- 尽管欧盟15+国家的半数以上的AF/AFL负担总体下降,但仍然存在显著的趋势差异.
- 治疗创新和国家特定因素,如医疗保健系统,社会经济地位和健康教育,可能有助于观察到的趋势.
- 老年女性代表着AF/AFL的脆弱人口,需要有针对性的风险评估和管理策略.
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