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Updated: Sep 12, 2025

Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel’s Cartilage
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在下骨发育过程中,梅克尔软骨形成需要PRDM对应物

Qootsvenma Denipah-Cook1, Bryanna V Saxton1, Kristin B Artinger2

  • 1Department of Biology, University of New Mexico, Albuquerque, NM, USA.

bioRxiv : the preprint server for biology
|August 8, 2025
PubMed
概括

基因组甲基转移酶PRDM3和PRDM16对于神经细胞分化为冠状细胞至关重要,确保正确的下骨发育和梅克尔软骨的形成. 它们的缺失破坏了Wnt/β-catenin信号传输,导致了面异常.

关键词:
梅克尔的软骨是一种软骨.这就是Mecom/Evi1.Prdm16 在线阅读Prdm3 在线阅读在Wnt/β-catenin中使用.头骨面部 面部 面部

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相关概念视频

Determination01:51

Determination

During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. Specification is demonstrated by removing a segment of an early embryo, “neutrally” culturing the tissue in vitro—for example, in a petri dish with simple medium—and then observing the derivatives. If the cultured region gives rise to cell types that it would normally generate in the embryo, this means that it is specified. In...
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