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尿道的主要大细胞神经内分泌癌:一个病例报告

Jianbai Chen¹, Xiaorong Mou², Zhiming Zhang³

¹Air Force Medical University, Xi'an, China.

Frontiers in urology

|August 8, 2025

概括

本病例报告详细介绍了第一例被记录的尿道初级大细胞神经内分泌癌 (LCNEC) 的病例. 这种罕见的尿道癌呈现出侵略性进展和不良预后,凸显了早期检测的必要性.

科学领域:

尿瘤学尿瘤学
病理学病理学病理学
医学案例报告病例报告

背景情况:

尿道的原发性神经内分泌癌非常罕见.
大细胞神经内分泌癌 (LCNEC) 之前没有在尿道中报告过.

研究的目的:

报告第一个记录的初级尿道LCNEC病例.
讨论与这种罕见瘤相关的侵袭性临床过程和不良预后.

主要方法:

一个43岁的女性患者的案例研究,患有一次性尿道LCNEC.
通过活检和病理学检查确认了诊断.
治疗包括彻底切除,然后对转移进行监测.

主要成果:

患者呈现出失尿症和疼痛,诊断出高度的LCNEC.
在手术后观察到淋巴结扩大和骨盆转移后的快速进展.
切除后486天,患者因扩散的转移而死亡.

结论:

主要尿道LCNEC是一种具有历史上不良预后的侵袭性恶性瘤.
这一案例强调了这种瘤的罕见性和攻击性.
早期诊断和干预对于潜在改善患者生存结果至关重要.

关键词:

案例报告案例报告大细胞神经内分泌癌细胞瘤预后预后预后进行激进囊切除术 (RC).尿道癌,尿道癌.

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