在2型糖尿病患者中,与疲劳相关的步行特征:横截面研究
Daisuke Iwaki1,2, Makoto Takahashi2, Toshihiro Kawae3
1Department of Clinical Practice and Support, Hiroshima University Hospital, Hiroshima, JPN.
Cureus
|August 8, 2025
概括
患有2型糖尿病的患者经历疲劳,表现出减弱的步行规律. 这种垂直加速异常可能会阻碍运动坚持,影响糖尿病管理.
科学领域:
- 生物力学 生物力学
- 内分泌学 在内分泌学.
- 老年学是指老年学的学科.
背景情况:
- 对于2型糖尿病的治疗,建议步行,但疲劳会限制运动.
- 2型糖尿病患者的疲劳会导致步态异常.
- 了解这些异常对于改善炼坚持至关重要.
研究的目的:
- 在2型糖尿病患者中识别与运动引起的疲劳相关的步态异常.
- 调查步行规律与疲劳水平之间的关系.
- 探索有助于在这个人群中增加炼障碍的因素.
主要方法:
- 对50名2型糖尿病患者的横截面研究,使用加速度计进行步态分析.
- 16米自由行测试以测量步态参数.
- 运动益处与障碍尺度用于将参与者分为疲劳和无疲劳组.
主要成果:
- 疲劳组表现出明显较低的垂直自相关系数 (ACVT),表明步行的规律性减少.
- 活动能耗 (AEE) 在疲劳组明显高于疲劳组.
- 多变量分析显示,年龄和ACVT是影响疲劳的重要因素.
结论:
- 步行时垂直加速的规律性降低是导致2型糖尿病疲劳的关键因素.
- 步行异常,特别是步行规律性下降,可能会成为持续炼的障碍.
- 针对步行规律的干预措施可能会改善2型糖尿病患者的运动能力和坚持.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.9K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.9K
Diabetes: Symptoms, Diagnosis, and Complications
694
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
694
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
35
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
35
Carbohydrate Metabolism
11.7K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.7K
Pathophysiology of Diabetes
1.2K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.2K


