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Updated: Sep 12, 2025

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基于网络的关于无细胞DNA产前查信息的比较:对性别发育护理差异的影响

Soojin Kim^1,2, Esther L Finney³, Ushasi Naha⁴

¹Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada.

Frontiers in urology

|August 8, 2025

概括

在网站上关于无细胞DNA (cfDNA) 产前查的信息往往来自非专业来源. 商业网站在报告选条件方面与一般搜索结果不同,突出需要提高准确性和DSD信息.

科学领域:

遗传学遗传学是一个
生物信息学是一种生物信息学.
医疗信息学医疗信息学

背景情况:

无细胞DNA (cfDNA) 产前查是一种非侵入性测试,用于检测母体血液中的胎儿遗传物质.
虽然用于确定性别,但关于意外后果的信息,如性别发展差异 (DSD) 检测是有限的.
关于cfDNA查的网站内容需要描述和比较.

研究的目的:

描述未来父母可获得的关于cfDNA产前查的网站信息.
为了比较商业测试公司网站和一般搜索结果之间的cfDNA相关内容.

主要方法:

从家长调查和谷歌搜索中使用NLP生成的术语进行系统的网站搜索.
通过遗传咨询师识别商业cfDNA测试公司 (CC) 网站.
收集关于网站特征和cfDNA信息的数据,然后进行统计分析.

主要成果:

确定了60个网站,其中包括11个独特的CC网站.
大多数网站 (73.7%) 的作者都是非专业人士.
与一般搜索结果相比,CC网站更有可能列出由cfDNA选的特定疾病 (例如,三症组21,18,13,形状,微切除) .

结论:

大多数在线cfDNA产前查信息来自非专业来源.
在商业和一般搜索网站的内容之间存在显著的差异,关于选条件.
提高cfDNA信息的可用性和质量,包括DSD检测,对于改善产前咨询至关重要.

关键词:

没有细胞的DNA (cfDNA)咨询咨询咨询咨询咨询性发育障碍性发育障碍性发育障碍胎儿的性别的确定.非侵入性的产前检测 (NIPT)患者教育患者教育发生性染色体倍化.基于网络的信息,基于网络的信息.

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