在儿童上道尿路疾病的内泌尿治疗
Darren Ha1,2, Kelly T Harris1,2,3, Kyle O Rove1,2,3
1Pediatric Urology Research Enterprise, Department of Pediatric Urology, Children's Hospital Colorado, Aurora, CO, United States.
Frontiers in urology
|August 8, 2025
概括
内泌尿外科为儿科上泌尿道疾病提供了较少的侵入性选择,如UPJ阻塞和结石病. 虽然有效,但对这些儿科内分泌治疗的最佳方法和并发症的证据仍然有限.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 内分泌学是什么?内分泌学是什么
- 最少侵入性的手术
背景情况:
- 内分泌学越来越多地用于儿科泌尿病的条件.
- 儿科内分泌学缺乏最佳方法和并发症数据.
- 疾病包括尿管皮交点 (UPJ) 阻塞,主要阻塞性大尿管和结石病.
研究的目的:
- 审查儿科UPJ阻塞,主要阻塞性大尿道和结石病的内分泌治疗方法.
- 为了突出儿童内分泌学的进步.
- 为了解决关于结果和并发症的证据缺乏的问题.
主要方法:
- 审查关于内分泌手术的现有文献.
- 对特定条件的成功率和并发症的分析.
- 讨论技术进步及其潜在影响.
主要成果:
- 像ERBD和内皮切除术这样的内泌尿系统选择在UPJ阻塞方面显示出可变的成功率 (76-100%).
- 大尿道的内泌尿外科成功率为70-90%,但可能存在囊尿道逆流的风险.
- 儿科骨髓灰质炎的URS和PCNL是有效的,具有可比的无石头率,但潜在的发病率差异.
结论:
- 内泌尿外科是对儿科上泌尿道疾病的有希望的,不那么侵入性的选择.
- 需要进一步的研究,以建立最佳的内分泌技术,并充分了解儿童的相关并发症.
- 技术进步可能会增加内分泌学的利用,作为儿科泌尿病学的一线治疗.
相关概念视频
Urinary Tract Calculi VI: Surgical Management
26
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
26
Urinary Tract Calculi III: Medical Management
23
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
23
Anatomy of the Genitourinary System I: Kidneys and Ureters
87
The upper urinary system comprises two kidneys and two ureters, which are crucial in filtering blood and forming urine.KidneysLocation and Structure:The kidneys are two bean-shaped organs positioned behind the peritoneum on either side of the spine.Kidneys are between the 12th thoracic (T12) and the 3rd lumbar (L3) vertebrae.The position of the liver causes the right kidney to sit slightly lower than the left.Protective Layers:Each kidney is enveloped in a tough, fibrous membrane called the...
87
Urinary Tract Infection I: Introduction
50
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
50
Urologic Endoscopic Procedure: Cystoscopic Examination
345
Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...
345
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
40
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
40


