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Updated: May 10, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
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在膀癌样本中发现的编码先天性免疫分子的基因突变是BCG和激动剂免疫治疗的潜在生物标志物

Nina Marí Gual Pimenta de Queiroz1, Fabio Mambelli1, Bruno Marques Silva2

  • 1Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Frontiers in urology
|August 8, 2025
PubMed
概括

像TLR9和TLR10这样的先天免疫基因的突变在膀癌 (BC) 中很常见. 这些遗传变化可以作为生物标志物来预测BC患者的结果,并指导个性化治疗策略.

关键词:
TCGA (癌症基因组图集计划) 是一个项目.生物标志物 生物标志物膀癌:膀癌是一种癌症.具有天生的免疫力.突变是发生在突变中的突变.

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