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Updated: Sep 12, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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临床和转化研究ivosidenib加nivolumab在先进的固体瘤的IDH1突变

Matthew K Nguyen1,2,3, Mark Jelinek1,4, Arjun Singh1,5

  • 1Hillman Cancer Center, UPMC, Pittsburgh, PA, USA.

medRxiv : the preprint server for health sciences
|August 8, 2025
PubMed
概括

这项研究发现,在IDH1突变的晚期固体瘤中,结合ivosidenib和nivolumab显示出有限的抗瘤活性,主要是疾病稳定. 需要通过免疫检查点抑制剂对IDH1抑制进行进一步的研究.

关键词:
一个IDH1一个IDH1这就是PD1 PD1.免疫疗法 免疫疗法它们可以被杀.这就是尼沃卢马布 (nivolumab).

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