提升和二产生临时性取决于性别的变化在日本 (Coturnix japonica) 胚胎发育
S K Winnicki1,2,3,4, M E Hauber1,2,3,5, R T Paitz6
1Department of Evolution, Ecology, and Behavior, School of Integrative Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
概括
母体类固醇会影响脊椎动物的生长. 在日本胚胎中,早期注射androstenedione (A4) 和 (T) 影响了生长速度和特定的身体特征,表明了性别和结构特定的反应.
科学领域:
- * 发育生物学 发育生物学
- * 内分泌学 在内分泌学.
- * 鸟类胚胎学 鸟类胚胎学
背景情况:
- *已知母体供应的类固醇会影响脊椎动物的生长速度.
- *以前注射个人激素到鸟蛋中的研究结果不一致,可能是由于时间,新陈代谢或自然激素相关性.
- *了解类固醇激素对胚胎发育的影响对于生殖生物学至关重要.
研究的目的:
- * 调查自然存在的安德罗斯坦 (A4) 和 (T) 对日本胚胎发育的影响.
- * 为了确定不同发育阶段的激素注射是否会影响生长,形态和蛋黄类固醇度.
- * 探索潜在化期间对类固醇激素暴露的潜在性别特异性反应.
主要方法:
- *肥沃的日本卵在化期的第0天和/或第6天被注射了androstenedione (A4) 和 (T) 或油控剂.
- *胚胎大小 (眼径,腿长,质量) 在第6天和第15天被测量.
- *卵黄类类固醇激素度在多个时间点 (第0,1,6,7和15天) 量化.
主要成果:
- *激素注射在治疗后24小时内没有显著改变黄蛋白类固醇度,也没有影响其他类固醇.
- *初始 (第0天) A4 + T注射减少了女性胚胎的眼睛直径和腿长,并在第6天减少了男性胚胎质量.
- *双注射 (第0天和第6天) 导致和翅膀变大,但在第15天,无论性别如何,总体质量减少.
结论:
- *日本的胚胎生长对安德罗斯坦 (A4) 和 (T) 水平的升高很敏感,特别是当在化初期给予时.
- *这些类固醇激素的作用是特定于胚胎的发育结构和性别.
- *这项研究强调了类固醇激素,胚胎发育和鸟类物种的性别决定之间的复杂相互作用.
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