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Jacopo Farina¹, Sant Kumar², Gianluca Campo¹

¹Cardiology Unit, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

|August 8, 2025

概括

静脉内静脉透术 (IVL) 用于支架不扩张,其安全性与前置IVL相提并论,但功能性结果较差. 这表明,静脉静脉注射器是不充分扩张的支架的可行救援策略.

科学领域:

心脏病学心脏病学
干预心脏病学干预心脏病学
医疗器械医疗器械

背景情况:

严重的冠状动脉化会导致支架不充分扩张,导致不良临床事件.
静脉内透症 (IVL) 已被确立为在支架前的化病变.
在治疗现有的支架不扩张方面,IVL的疗效和安全性尚未得到很好的定义.

研究的目的:

为了比较使用IVL前期与内静脉治疗治疗支架不扩张的结果.
评估皮肤穿冠状动脉干预 (PCI) 中静脉静脉注射器的功能结果和安全性.

主要方法:

一项多中心的回顾性研究包括了166名接受PCI和IVL的患者.
患者被分为前期IVL (支架前) 和静脉IVL (不扩张) 组.
结果包括基于定量流量比率的透支体梯度 (QFR-TSG) > 0,目标血管衰竭和主要不良心血管事件 (MACE),分析与治疗权重的逆概率 (IPTW) 和卡普兰-梅尔曲线.

主要成果:

内静脉IVL组的糖尿病发病率更高 (49.4%对19.5%).
内静脉IVL与QFR-TSG>0的更高率 (77.2%对60.9%,p=0.036) 有关.
在IPTW后,静脉静脉注射并没有显著增加MACE风险 (OR 1.11),并且在3.7年内,MACE无生存时间在组之间是相似的.

结论:

与前置IVL相比,内静脉IVL表现出较差的功能结果.
内静脉IVL似乎是治疗支架扩张不足的安全选择.
使用IVL内置支架可以作为未扩张支架的有价值的救援疗法.

关键词:

静脉内静脉三症是什么意思静脉内静脉体内三.支柱下扩张的情况.

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