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Updated: Sep 12, 2025

Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae
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Published on: February 25, 2022

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优势阴性TDP-43异型受ALS相关RNA结合蛋白调节

Minami Hasegawa-Ogawa1, Asako Onda-Ohto1,2, Takumasa Nakajo1

  • 1Division of Regenerative Medicine, Research Center for Medical Sciences, The Jikei University School of Medicine, Tokyo, Japan.

The Journal of cell biology
|August 8, 2025
PubMed
概括

研究人员确定了一种主导负的TDP-43 (TARDBP) 异型,并发现与ALS相关的蛋白调节其表达. 这个网络的失调有助于神经退行性疾病的发病.

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