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Updated: Sep 12, 2025

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels
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具有独特折叠的蜘蛛毒可以选择性地阻断Shaker类型的通道

Alexey I Kuzmenkov1, Valentina A Iunusova2, Vladislav A Lushpa2

  • 1Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia. aleksey.kuzmenkov@gmail.com.

Cellular and molecular life sciences : CMLS
|August 8, 2025
PubMed
概括

研究人员发现了新的蜘蛛毒素,虫毒素,可以选择性地阻断Shaker型通道 (KV1). 这些毒素具有独特的二硫化物净化发针结构,为生物工程应用提供了潜力.

关键词:
阻塞器 阻塞器 阻塞器硫化二氧化物是二硫化物中的一种.抑制剂 囊结的抑制剂离子通道 离子通道神经毒素是一种神经毒素.空间结构 空间结构

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