在艾滋病毒感染和没有艾滋病毒的老年人中,步行速度和神经认知
Evelyn Iriarte1, Raymond Jones2, Crystal X Wang3
1College of Nursing, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
AIDS (London, England)
|August 8, 2025
概括
与没有艾滋病毒的人 (PWoH) 相比,感染艾滋病毒的老年人 (PWH) 的步行速度较慢,神经认知能力较差. 步行速度较慢与PWH的认知缺陷有关,特别是在口语流方面.
科学领域:
- 神经学 神经学
- 老年学是一门学科.
- 传染性疾病 传染性疾病
背景情况:
- 携带艾滋病毒的老龄化带来了独特的健康挑战.
- 神经认知障碍是艾滋病毒感染者 (PWH) 的已知的并发症.
- 步行速度是老年人整体健康和认知功能的敏感指标.
研究的目的:
- 研究艾滋病毒感染和不感染的老年人的步行速度和神经认知之间的关联.
- 为了比较艾滋病毒感染者 (PWH) 和没有艾滋病毒感染者 (PWoH) 之间的步行速度和认知表现.
- 为了确定受PWH步行速度影响的特定神经认知领域.
主要方法:
- 一项涉及285名艾滋病毒感染者 (PWH) 和214名没有艾滋病毒感染者 (PWoH) 的跨截面研究,年龄在50岁及以上.
- 用标准化检查测量了步行速度.
- 综合的神经认知评估评估了全球和特定领域的认知功能.
主要成果:
- 与没有艾滋病毒的人 (PWoH) 相比,艾滋病毒感染者 (PWH) 的步行速度明显减慢.
- 步行速度较慢与全球神经认知能力较差以及PWH语言流性,执行功能,处理速度和运动技能的缺陷有关.
- 一个显著的相互作用表明,根据艾滋病毒状态,步行速度对口语流有不同的影响.
结论:
- 步行速度与老年人的神经认知功能密切相关,特别是在艾滋病毒感染者 (PWH) 中.
- 这些发现表明需要进一步进行纵向研究,以了解因果关系.
- 步行速度可能具有作为PWH认知变化的临床查工具的潜力.
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